Flt3L therapy increases the abundance of Treg-promoting CCR7<sup>+</sup> cDCs in preclinical cancer models.

Front Immunol · 2023 · PMC10445485 · PMID 37622122

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showed a trendno p-value reported

Most importantly, when culturing naive T cells with either CD81 + migcDC1s or other migDCs (composed of CD81 - migcDC1s and migcDC2s) sorted from Flt3L-treated tumors, the CD81 + migcDC1s showed a trend to more potently drive the differentiation of naive T cells into Tregs ( Figure 3E ).

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