Anti-Inflammatory Effects of Serotonin Receptor and Transient Receptor Potential Channel Ligands in Human Small Intestinal Epithelial Cells.

Curr Issues Mol Biol · 2023 · PMC10453699 · PMID 37623246

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Regarding capsaicin, a reduction in COX-2 levels was observed only at a dose of 0.5 μM compared to the TNF-α/IFN-γ group ( p < 0.001, Figure 6 D), although both 0.1 and 1 μM showed a trend towards decreased normalized COX-2/GAPDH levels ( p = N.S., Figure 6 D).

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