Ezrin Inhibition Overcomes Acquired Resistance to Vemurafenib in BRAFV600E-Mutated Colon Cancer and Melanoma Cells In Vitro.

Int J Mol Sci · 2023 · PMC10454476 · PMID 37629086

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a marked trendno p-value reported

We observed a marked trend towards increased expression of total ezrin and phospho-ezrin in resistant melanoma cells under baseline conditions, which indicates that increased abundance of ezrin could be potentially linked with the vemurafenib-resistant phenotype in BRAFV600E-mutated melanoma cells. 2.6.

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