Mutations of <i>BRCA1</i>, <i>BRCA2</i>, and <i>PALB2</i> Genes in Breast Tumor Tissue: Relationship with the Effectiveness of Neoadjuvant Chemotherapy and Disease Prognosis.

Further, it was shown that in the general group of patients with the presence of deletions (25.5%, 12/47 patients) and amplifications (31.9%, 15/47 patients) at the level of a pronounced trend ( p = 0.07), an objective response is most often observed on treatment (complete and partial regression), compared with the group without response (stabilization and progression), where the frequency of deletions (10.5%, 2/19 patients) and amplifications (15.8%, 3/19 patients) is lower, more than twice ( Table 2 ).

also in 61 other papers

The differences are not statistically significant, but a strong trend is shown at p = 0.07 ( Figure 6 E).

also in 1,049 other papers

All statistically significant associations have a borderline significance level, which can most likely be explained by a small sample for this analysis.

also in 1,199 other papers