Artificial oocyte activation with Ca<sup>2+</sup> ionophore improves reproductive outcomes in patients with fertilization failure and poor embryo development in previous ICSI cycles.

Front Endocrinol (Lausanne) · 2023 · PMC10455927 · PMID 37635975

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did not reach statistical significanceno p-value reported

In the PED group, the fertilization rate, implantation rate and clinical pregnancy rate were highly increased after AOA, and the top-quality embryo rate was increased slightly after AOA treatment compared with their previous ICSI cycle without AOA but did not reach statistical significance.

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