Molecular Imaging Investigations of Polymer-Coated Cerium Oxide Nanoparticles as a Radioprotective Therapeutic Candidate.

Tumor volume changes were not statistically significant between irradiated mice versus either of the CONP treatments, though uncoated CONPs showed a trend toward poorer tumor control ( p = 0.07 vs. irradiation alone). 3.3. pH-Dependent Redox Reaction of PAA-CONP PAA-CONPs in buffered solutions of pH 7.4, 7.0, and 6.6 demonstrate decreased redox capacity with decreasing pH and are presented in Figure 3 .

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