The kisspeptin-1 receptor antagonist peptide-234 aggravates uremic cardiomyopathy in a rat model.

Consequently, the LV end-systolic and end-diastolic internal diameters showed a trend toward a decrease (p = 0.16 and p = 0.09, respectively), and the fractional shortening was significantly increased in the CKD-only group compared to the sham group (Table 1 ).

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