On average, female tgfbr2 flox/flox /Col2CreER T +/− (TCs) were heavier than female itga1 -null/ tgfbr2 flox/flox /Col2CreER T +/− (aTCs), although this difference did not reach statistical significance ( Fig. 2 ).
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Depleting transforming growth factor beta receptor 2 signalling in the cartilage of <i>itga1</i>-null mice attenuates spontaneous knee osteoarthritis.
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