Eight weeks after surgery, the LV ( i.e., left ventricular internal diameter at end-diastole, LVIDd; left ventricular internal diameter at end-systole, LVIDs ) in MR and MR + PIMO rats appeared to be increased but did not reach statistical significance when compared with sham rats (Supplement Tables 1 and 2 ).
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Pimobendan prevents cardiac dysfunction, mitigates cardiac mitochondrial dysfunction, and preserves myocyte ultrastructure in a rat model of mitral regurgitation.
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