Targeted delivery of a PD-1-blocking scFv by CD133-specific CAR-T cells using nonviral Sleeping Beauty transposition shows enhanced antitumour efficacy for advanced hepatocellular carcinoma.

BMC Med · 2023 · PMC10464109 · PMID 37635247

Europe PMC DOI

hedged sentence

0.0410

closest p · 0.8× alpha

0.0410

boldest claim

The sentences

showed a trendP = 0.041actually significant

Results A univariate analysis showed that CD133 expression in male patients at the late stage (II and III) was significantly associated with worse progression-free survival (PFS) ( P = 0.0057) and overall survival (OS) ( P = 0.015), and a multivariate analysis showed a trend toward worse OS ( P = 0.041).

also in 25,348 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.