Ischemic stroke risk factors not included in the CHADS-VASC score in patients with non-valvular atrial fibrillation.

Arq Neuropsiquiatr · 2023 · PMC10468251 · PMID 37567570

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

The ROC curve analysis showed that a CRP threshold value of 3.5 mg/dL at admission had a sensibility of 61.5%, a specificity of 78%, a positive predictive value of 73.5% and a negative predictive value of 66.9% for the occurrence of AIS, but this result did not reach statistical significance (global AUC = 0.71; p = 0.06).

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borderline significantp = 0.061so close (0.05 < p ≤ 0.1)

The difference was statistically significant (Log-Rank test, χ 2 (1; N = 114) = 27.6 p <0.001). The other prognostic factor for global mortality was COPD (Log-Rank test; χ 2 (1, N = 114) = 4.45; p =0.035) ( Figure 2 ). After adjusting for age, sex, CHA2DS2-VASc score and the use of an anticoagulant treatment, we found a statistically significant difference between both groups for weight (79 ± 20 kg vs 84 ± 23 kg; p = 0.036), and a borderline significant difference for CRP (6 ± 14 vs. 3 ± 1; z = 1.87373 ; p = 0.061).

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