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Metformin does not slow cyst growth in the PCK rat model of polycystic kidney disease.

Physiol Rep · 2023 · PMC10471794 · PMID 37653564

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In a randomized trial of MET in ADPKD patients (TAME PKD), the annual change of GFR did not reach statistical significance in the MET‐treated group (Perrone et al., 2021 ).

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