Recent increase in low complexity polygenomic infections and sialic acid-independent invasion pathways in Plasmodium falciparum from Western Gambia.

Comparison of invasion phenotypes across the 3 years showed a trend towards increased neuraminidase inhibition between 2015 to 2021 (mean: 2015 = 22.21%, 2016 = 26.69%, and 2021 = 31.6%) but the differences were not statistically significant (Kruskal-Wallis test, P = 0.3) (Fig. 4 A).

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These correlations among age, parasitaemia, and enzyme treatments were not statistically significant, although marginally significant for HT inhibition and age (0.05) (Fig. 5 ).

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