Phase II randomised, placebo-controlled, clinical trial of interleukin-1 receptor antagonist in intracerebral haemorrhage: BLOcking the Cytokine IL-1 in ICH (BLOC-ICH).

Mean OED was similar at baseline and increased less in the anakinra group ( Figure 2 , Table 2 ), but after adjusting for baseline, this did not reach statistical significance (anakinra vs placebo, adjusted OED difference at 72 h: −0.05 [−0.17, 0.06], p = 0.336).

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