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Molecular epidemiology and clinical characteristics of enteroviruses associated HFMD in Chengdu, China, 2013-2022.

Virol J · 2023 · PMC10476316 · PMID 37661256

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showed a trendno p-value reported
2 A), the annual total number of HFMD cases showed a trend of initially increasing and then decreasing, reaching its peak in 2016 and its lowest point in 2022.

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a decreasing trendno p-value reported
The overall number of HFMD cases showed a decreasing trend, among which EV-A71 infection almost disappeared, instead, CV-A6 infection accounted for more than 50%.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.