Bacterial immunotherapy is highly effective in reducing recurrent upper respiratory tract infections in children: a prospective observational study.

Although the distribution of the predominant etiologies (AOM or PT) was uneven (Pearson’s chi-square P = 0.047), the differences of other socio-demographic or clinical characteristics between the study cohorts did not reach statistical significance, with the exception of the score of school absenteeism, which was higher in the auto-vaccines cohort (Mann–Whitney’s U test P = 0.004, Table 2 ).

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