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Inhibition of nonsense-mediated mRNA decay reduces the tumorigenicity of human fibrosarcoma cells.

NAR Cancer · 2023 · PMC10480688 · PMID 37681034

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Even though these differences in mitotic activity and necrosis did not reach statistical significance, they suggest that the tumors formed by SMG7KO cells grew more slowly than those formed by parental HT1080 cells, and that this phenotype was partially reverted in the RESCUE cells.

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