The mutational landscape of the adult healthy parous and nulliparous human breast.

Nat Commun · 2023 · PMC10482899 · PMID 37673861

Europe PMC DOI

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0.1780

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0.1780

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did not reach statistical significancep = 0.178not close (p > 0.1)

In the analyzed nulliparous epithelial samples ( n = 10), the number of substitutions (single, double, and triple nucleotide changes) significantly increased with age ( R = 0.67, p = 0.033), a tendency which was weaker and did not reach statistical significance in the parous epithelium ( n = 13, R = 0.40, p = 0.178, Fig. 3 ).

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