The relative abundance of live, CD45+ cells (leukocytes) showed a trend consistent with our histology data, with Ldha LysM−/− mice exhibiting decreased abundance of leukocytes at 4 wpi infection and increased abundance at 30 wpi, relative to WT controls (Fig. 3A ).
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NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis.
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