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FoxO3 normalizes Smad3-induced arterial smooth muscle cell growth.

Front Physiol · 2023 · PMC10483145 · PMID 37693008

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a marked trendp = 0.08so close (0.05 < p ≤ 0.1)
Smad3-infected cells in the Ad-Smad3 and Ad-Smad3/Ad-FoxO3 groups showed significant increases in phosphorylated and total Smad3 in the cytoplasm ( Figures 6C, D ), a marked trend ( p = 0.08) for increased phosphorylated Smad3 in the nucleus ( Figure 6E ), and significantly increased total Smad3 in the nucleus ( Figure 6F ) compared to Ad-GFP cells.

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