The Role of Toll-like Receptor-4 in Macrophage Imbalance in Lethal COVID-19 Lung Disease, and Its Correlation with Galectin-3.

Int J Mol Sci · 2023 · PMC10487501 · PMID 37686069

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an interesting trendno p-value reported

Comparisons were not statistically significant, due to heterogeneous variability of CD163 (+) myeloid derived macrophages in different deceased subjects, but showed an interesting trend, as compared to the limited number of samples examined.

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showed a trendno p-value reported

Nevertheless, our study showed a trend to TLR-4 up-regulation in lungs of a subgroup patients with lethal COVID-19, when compared to the control group of SARS-CoV-2 negative lungs.

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