Barely Significant
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Upregulation of Orai Channels Contributes to Aging-Related Vascular Alterations in Rat Coronary Arteries.

Int J Mol Sci · 2023 · PMC10487684 · PMID 37686206

Europe PMCDOI
1
hedged sentence
0.8243
closest p · 16.5× alpha
0.8243
boldest claim

The sentences

did not reach statistical significancep = 0.8243not close (p > 0.1)
The potentiating effects of YM-58483 on endothelial vasodilation cannot be simply attributed to a potential effect on precontraction of 5-HT, since the effect of YM-58483 at 10 μM on the precontraction level in coronary arteries from old rats did not reach statistical significance either in terms of absolute values (4.68 ± 0.47 mN vs. 5.38 ± 1.03 mN for YM-58483 and the vehicle, respectively, n = 12, p = 0.8243) or in terms of the percentage of K + -induced contractions (71.89 ± 7.26% vs. 79.55 ± 6.67% for YM-58483 and the vehicle, respectively, n = 12, p = 0.3820).

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