Tissue and Circulating MicroRNAs 378 and 142 as Biomarkers of Obesity and Its Treatment Response.

Int J Mol Sci · 2023 · PMC10487855 · PMID 37686231

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0100

boldest claim

The sentences

did not reach statistical significancep = 0.01actually significant

During sibutramine therapy, expression of miR-378 in SAT tended to increase but did not reach statistical significance, while in plasma, a reliable increase in the miR-378 level was revealed ( p = 0.01) ( Figure 1 C,D).

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an increasing trendno p-value reported

We observed a significant increase in its level in the circulation but only an increasing trend in SAT, which may reflect the systemic action of the drug.

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