The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats.

Int J Mol Sci · 2023 · PMC10487893 · PMID 37686275

Europe PMC DOI

hedged sentences

0.0005

closest p · 0.0× alpha

0.0500

boldest claim

The sentences

highly significantp < 0.0005actually significant

In all these comparisons, the difference between control antibody and fremanezumab was highly significant (F 1,62/64 = 21.40–23.68, p < 0.0005) but there was no difference between the three trigeminal partitions V1-V3 (F 2,62 = 0.80, p = 0.45), between females and males (F 1,64 = 0.65, p = 0.42) and between different waiting times (F 1,64 = 0.64, p = 0.43).

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weakly significantp < 0.05actually significant

There was also a weakly significant interaction of the factors antibody, sex and day (F 2,40 = 4.98, p < 0.05).

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