An important trend was observed while analyzing elongation patterns of monounsaturated and diunsaturated WEs (MUWEs and DUWEs, correspondingly): the analysis demonstrated a steady and statistically significant downregulation of longer-chain MUWEs with m / z values at, or above, 619 (i.e., ≥C 42 H 82 O 2 ) and DUWEs with m / z values of above 673 (>C 46 H 88 O 2 ) in aged mice ( Figure 6 D,E).
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Dysregulation of Lipid Metabolism in Aging Meibomian Glands and Its Molecular Markers.
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