Cortical Mechanisms Underlying Immersive Interactive Virtual Walking Treatment for Amelioration of Neuropathic Pain after Spinal Cord Injury: Findings from a Preliminary Investigation of Thalamic Inhibitory Function.

J Clin Med · 2023 · PMC10488675 · PMID 37685810

Europe PMC DOI

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0.6440

closest p · 12.9× alpha

0.6440

boldest claim

The sentences

approached significancep = 0.644not close (p > 0.1)

There was a decrease in NPS ratings of pain severity from pre- to post-intervention that approached significance (mean PDI PRE Intervention: 19 ± 10; mean PDI POST Intervention ± SD POST Intervention: 21 ± 20; t = −0.486, df = 6, p = 0.644; mean Pain Interference PRE Intervention: 2.1 ± 2.3; mean Pain Interference POST Intervention ± SD POST Intervention: 0.6 ± 0.8; t = 3.161, df = 6, p = 0.052).

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a marginal trendno p-value reported

Participants showed a marginal trend toward a significant decrease in NPS ratings of pain severity collected prior to and following the intervention (mean NPS ± SD PRE Intervention: 40.6 ± 15; mean NRS ± SD POST Intervention: 25.0 ± 16; t = 2.408, df = 6, p = 0.053; Figure 3 , individual NPS values are represented in Table 2 ).

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