Impact of 12 Weeks of Vitamin D<sub>3</sub> Administration in Parkinson's Patients with Deep Brain Stimulation on Kynurenine Pathway and Inflammatory Status.

Nutrients · 2023 · PMC10490466 · PMID 37686871

Europe PMC DOI

hedged sentences

0.0620

closest p · 1.2× alpha

0.0670

boldest claim

The sentences

a strong trendp = 0.062so close (0.05 < p ≤ 0.1)

In KYNA there was no significant difference, but a strong trend p = 0.062 (0.69 ± 1.54 in the VitD group compared to −0.23 ± 1.31 in the PL group; Figure 4 a) was observed.

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an increasing trendp = 0.067so close (0.05 < p ≤ 0.1)

However, although an increasing trend in the VitD group was observed (6.60 ± 1.42 versus 7.29 ± 1.58 ng/mL, p = 0.067; Figure 2 b), there was no notable difference in the PL group (7.23 ± 2.10 at T0, 7.00 ± 2.43 ng/mL at T1; Figure 2 b).

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a decreasing trendno p-value reported

Moreover, the overall inflammatory state measured with high sensitivity C-reactive protein after the administration showed a decreasing trend [ 14 ].

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