Patients with low IVKI had a numerically higher rate of transformation to blast crisis than patients with high IVKI, but this did not reach statistical significance (7.7% vs 3%, OR 2.71, 95% CI 0.65–10.39, p = 0.19, Supplementary Fig. 3C ).
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Adverse outcomes for chronic myeloid leukemia patients with splenomegaly and low in vivo kinase inhibition on imatinib.
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0.1900