Neurofilament light chain as a mediator between LRRK2 mutation and dementia in Parkinson's disease.

NPJ Parkinsons Dis · 2023 · PMC10497522 · PMID 37699957

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did not reach statistical significanceno p-value reported

It was found that SNCA -PD had higher serum NfL at baseline after adjustment compared to iPD, but the difference between the other groups did not reach statistical significance, consistent to some extent with our hypothesis.

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failed to reach significanceno p-value reported

The differences between SNCA -PD and GBA -PD ( β = −6.405, p = 0.032) and between SNCA -PD and LRRK2 -PD ( β = −5.715, p = 0.014) failed to reach significance after Bonferroni correction.

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