Purging due to self-fertilization does not prevent accumulation of expansion load.

PLoS Genet · 2023 · PMC10501686 · PMID 37656747

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Only in an additional set of simulations of fully additive mutations increased selfing showed a trend of further improving fitness after an expansion ( S1(C) Fig ), however, we believe that such a mutational model of fully additive mutations is unlikely to accurately represent nature [ 69 , 70 ].

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