Micronized Acellular Matrix Biomaterial Leverages Eosinophils for Postinfarct Cardiac Repair.

Levels of eotaxin, a key eosinophil chemoattractant, were evaluated at 3 days post–mSIS-ECM delivery before their recruitment in the noninfarct mouse model to assess the local regulation of eosinophil recruitment to the pericardial space At this timepoint, eotaxin analysis showed a trend for increased eotaxin concentrations in the pericardial fluid of the mSIS-ECM treatment group relative to the control group ( Supplemental Figure 3D ).

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