Incidence, risk factors and outcomes of checkpoint inhibitor-induced liver injury: A 10-year real-world retrospective cohort study.

17 , 44 A retrospective cohort showed that the incidence of all grade liver toxicity is highest in patients 50–64 years old (10.6%) compared with 3.1% in the 65–74 age group and 4.3% in the age group >74; however, the difference did not reach statistical significance. 44 Another retrospective study reported a comparable proportion of liver metastases between patients with and without ChILI. 17 Although baseline NLR was significantly different between patients with and without ChILI, a similar observation recently reported, 21 it was not independently associated with ChILI in multivariable analysis.

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