Sex and anti-inflammatory treatment affect outcome of melanoma and non-small cell lung cancer patients with rheumatic immune-related adverse events.

In the combined ICI groups we found a small trend to more de novo R-irAEs (~80% vs 93%), higher rates of reported myalgia, myositis and (mostly clinically irrelevant) CK elevation, but lower rates of tenosynovitis.

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Interestingly, in female patients we observed a strong trend towards more frequent joint involvement and/or back pain, which probably explains why more women received DMARDs.

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