Impact of body mass index and its change on survival outcomes in patients with early breast cancer: A pooled analysis of individual-level data from BCIRG-001 and BCIRG-005 trials.

Breast · 2023 · PMC10512096 · PMID 37429049

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

marginally significantP = 0.052so close (0.05 < p ≤ 0.1)

As for BMI change, a BMI loss >10% had a marginally significant impact on DFS (HR = 1.87, 95%CI 1.00–3.50, P = 0.052), and it predicted significantly worse OS (HR = 2.15, 95%CI 1.01–4.57, P = 0.047) ( Fig. 2 C and D, Supplementary Table S1 ).

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failed to reach statistical significanceno p-value reported

However, this nonlinear relationship failed to reach statistical significance ( P for non-linearity = 0.111).

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