Intraoperative Fluorophores: An Update on 5-Aminolevulinic Acid and Sodium Fluorescein in Resection of Tumors of the Central Nervous System and Metastatic Lesions-A Systematic Review and Meta-Analysis.

Tomography · 2023 · PMC10514891 · PMID 37736977

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highly significantno p-value reported

In another recent study regarding Grade III tumor resection, OS was not significantly improved in 5-ala-assisted surgery compared to the control groups; however, a subgroup analysis showed that patients with 5-ala-guided resection who underwent GTR showed a highly significant improvement in OS compared to the control group [ 57 ].

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did not reach statistical significanceno p-value reported

Though our analysis did not reach statistical significance when comparing the rate of fluorescence by tumor type, we did observe that LGG demonstrated remarkably different fluorescence rates and patterns to other CNS tumors.

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