Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.

Front Immunol · 2023 · PMC10516574 · PMID 37744358

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a negative trendno p-value reported

In three participants (101 with a positive trend, and 105 and 107 with a negative trend), total HIV-1 DNA was quantified ( Figure 3G ).

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a positive trendno p-value reported

caRNA levels in ALN-treated participants 101, 102 and 103 showed a positive trend in caRNA levels from basal to available follow up time points, while participant 104 had a transient increase at week 2 after the intervention.

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