slightly significantp value = 0.035
By stratifying patients according to the ICR/GIE classification of week 12 biopsies we found a slightly significant difference ( p value = 0.035, log-rank test) in OS and in PFS ( p value = 0.022, log-rank test) between the High-ICR/GIE and the High-ICR/Non-GIE group (Fig. 6c and Supplementary Fig 9b ).