Barely Significant
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A CaCO<sub>3</sub>-based nanoplatform with sonodynamic and tumor microenvironment activated for combined in vitro cancer therapy.

Transl Oncol · 2023 · PMC10518365 · PMID 37729741

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a significant trendno p-value reported
Further mining of gene clustering heat map, found that the HIF-1-related pathway had a significant trend of inhibited expression in the QD@Ca/M L-Arg +US group, which was consistent with the pattern of HIF-1α in hypoxic cancer cells that was suppressed by ONOO − in the previous report.

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