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Effect of melatonin on otoprotection in rodents: a systematic review with meta-analysis.

Braz J Otorhinolaryngol · 2023 · PMC10518499 · PMID 37451174

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showed a trendno p-value reported
At more severe frequencies (1500 Hz, 2000 Hz, 3000 Hz, and 4000 Hz), no protective effect of melatonin was demonstrated, although the meta-analysis showed a trend towards this effect.

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