Out of the four studies favouring estrogen, two showed a statistically significant difference [ 30 , 31 ], while in the other two studies, the difference did not reach statistical significance [ 28 , 29 ].
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Comparison of the Efficacy of Vaginal Hyaluronic Acid to Estrogen for the Treatment of Vaginal Atrophy in Postmenopausal Women: A Systematic Review.
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