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Association between CYP3A4/CYP3A5 genetic polymorphisms and treatment outcomes of atorvastatin worldwide: is there enough research on the Egyptian population?

Eur J Med Res · 2023 · PMC10523700 · PMID 37759317

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In addition, in the M445T allele carriers, a higher LDL-C lowering response to atorvastatin was detected among 340 Americans suffering from primary hypercholesterolemia, although it failed to reach statistical significance [ 24 , 34 ].

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