Is the Development of Ascites in Alcoholic Liver Patients Influenced by Specific KIR/HLA Gene Profiles?

Biomedicines · 2023 · PMC10525207 · PMID 37760846

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did not reach statistical significanceno p-value reported

However, this difference did not reach statistical significance despite showing a lower frequency in our patient population than in controls (46.3% and 52.5%, respectively).

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highly significantno p-value reported

In addition, the KIR2DL1(+)/S1(-)/C2C2 genotype, which is associated with susceptibility to melanoma and lymph node metastasis [ 51 , 52 ], was also observed with a highly significant increase in homozygous KIR2DL3/HLA-C1 in patients with Crohn’s disease, confirming the relevance of the KIR2DL2/KIR2DL3 genes and their interaction with HLA-C and disease.

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