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Bile Acid Sequestration via Colesevelam Reduces Bile Acid Hydrophobicity and Improves Liver Pathology in <i>Cyp2c70</i><sup>-/-</sup> Mice with a Human-like Bile Acid Composition.

Biomedicines · 2023 · PMC10526181 · PMID 37760936

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However, the reduction in the amount of cholangiocytes in livers that was achieved with 3 weeks of colesevelam treatment in KO mice did not reach statistical significance ( Figure 4 E). 3.5.

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