Reducing the Invasiveness of Low- and High-Grade Endometrial Cancers in Both Primary Human Cancer Biopsies and Cell Lines by the Inhibition of Aquaporin-1 Channels.

Cancers (Basel) · 2023 · PMC10526386 · PMID 37760476

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showed a trendno p-value reported

In MFE-280 cells, AqB011 at 60 μM (the maximum dose tolerated in this cell line) showed a trend towards reduced invasion (~18%; not significant), and 5-PMFC at 0.5 mM inhibited invasion by ~77%.

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