Cardiac Progenitor Cell Exosomal miR-935 Protects against Oxidative Stress.

Cells · 2023 · PMC10528297 · PMID 37759522

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showed a trendno p-value reported

Only NOTCH1 showed a trend to be upregulated upon miR-935 inhibitor (INH) transfection.

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highly significantno p-value reported

Proteomics demonstrated a highly significant representation of cardiovascular development functions and angiogenesis in CPC exosomes, and RNAseq analysis yielded about 350 different miRNAs; among the exo-miR SEL population, miR-935 was confirmed as the miRNA most significantly up-regulated; interestingly, miR-935 was also found to be preferentially expressed in mouse primary cardiac Bmi1 +high CPC, a population highly enriched in progenitors.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.