A decreasing trend was also observed when normalizing the results to EV protein content (Fig. 3 D, right graph) but the changes were not statistically significant.
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Extracellular Vesicle-Serpine-1 Affects Neural Progenitor Cell Mitochondrial Networks and Synaptic Density: Modulation by Amyloid Beta and HIV-1.
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An increasing trend in the HIV-EV group was also observed although values in the No EV group were scattered (Fig. 4 D).
While ECAR was slightly lower in the PAI039 group as compared to control, these changes did not reach statistical significance (Supplementary Fig. 1 C).