Association between Immunogenicity of a Monovalent Parenteral P2-VP8 Subunit Rotavirus Vaccine and Fecal Shedding of Rotavirus following Rotarix Challenge during a Randomized, Double-Blind, Placebo-Controlled Trial.

Viruses · 2023 · PMC10536230 · PMID 37766217

Europe PMC DOI

hedged sentence

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

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did not reach statistical significancep = 0.062so close (0.05 < p ≤ 0.1)

Association between Immune Responses and Fecal Shedding of Rotavirus among P2-VP8-P[8] Recipients One month after the third P2-VP8-P[8] vaccine dose, anti-P2-VP8-P[8] IgA seroresponse was higher in shedders (93.3%) compared to non-shedders (69.3%), although this did not reach statistical significance ( p = 0.062; Table 1 ).

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