A Species-Specific Anti-Human P2X7 Monoclonal Antibody Reduces Graft-versus-Host Disease in Humanised Mice.

Livers from mice treated with the isotype control mAb showed a 2.2-fold increase in signs of leukocyte infiltration and tissue damage compared to the livers from the anti-hP2X7 mAb-treated mice, but this increase did not reach statistical significance ( p = 0.49) ( Figure 4 A).

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