Barely Significant
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Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study.

Dermatol Ther (Heidelb) · 2023 · PMC10539230 · PMID 37731086

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nominally significantno p-value reported
However, non-significant improvements from baseline in PPP ASI and nominally significant improvements in PPP PGA scores were observed with spesolimab.

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