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Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with <i>MLL</i> rearrangement or <i>NPM1</i> mutation to venetoclax.

Haematologica · 2023 · PMC10543165 · PMID 37102614

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While these results are consistent with the above-reported in vitro data, this trend did not reach statistical significance.

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